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Inter Milan vs Shakhtar Donetsk Prediction and Betting Tips | UEFA Champions League Gameweek 3

Inter Milan welcome Shakhtar Donetsk to Stadio Giuseppe Meazza in Milano in UEFA Champions League Gameweek 3 action on Wednesday 21 October 2026.

Inter Milan have played 7 matches in UEFA Champions League this season, scoring 3.0 and conceding 1.3 goals a game and winning 86% of them. At home they average 3.8 goals scored and 1.5 conceded over 4 matches, with a 67% win rate. Shakhtar Donetsk have played 2 matches in UEFA Champions League this season, scoring 2.0 and conceding 1.0 goals a game and winning 50% of them. Away from home they average 1.0 goals scored and 1.0 conceded over 1 match, with a 0% win rate.

On the bookmakers' prices, with their margin taken out, Inter Milan are clear favourites at 75%, with the draw at 15% and Shakhtar Donetsk at 10%.

The odds

Inter Milan1.2075%
Draw6.2015%
Shakhtar Donetsk9.0010%

Decimal odds; the percentages are the chances the prices imply once the bookmaker's margin (10.6% on this market) is taken out. The main Asian handicap is Inter Milan -2 at 1.95, Shakhtar Donetsk at 1.95. The main goals line is 3.5: over 1.86, under 2.02, which gives over 52%.

Inter Milan: form and key numbers

In style Inter Milan keep the ball, press high, cross a lot.

Shakhtar Donetsk: form and key numbers

Inter Milan vs Shakhtar Donetsk: season averages side by side

Inter MilanPer matchShakhtar Donetsk
2.81Expected goals (xG)0.92
1.10xG conceded–
3.00Goals2.00
21.7Shots10.0
7.3Shots on target3.0
3.7Big chances missed0.5
79.5Pressure share %–
16.3Tackles20.0
8.1Fouls15.5
1.6Yellow cards3.5

Season averages per match from Sportmonks, over 7 and 2 measured matches.

Inter Milan vs Shakhtar Donetsk: head-to-head stats and key numbers

Head to head

In their last 6 meetings Inter Milan won 2, drew 4 and lost 0.

DateHomeScoreAway
24 Nov 2021Inter Milan2 – 0Shakhtar Donetsk
28 Sep 2021Shakhtar Donetsk0 – 0Inter Milan
9 Dec 2020Inter Milan0 – 0Shakhtar Donetsk
27 Oct 2020Shakhtar Donetsk0 – 0Inter Milan
17 Aug 2020Inter Milan5 – 0Shakhtar Donetsk
24 Aug 2005Inter Milan1 – 1Shakhtar Donetsk

Players to watch

Inter Milan

Scouting spotlight: Marcus Thuram

Marcus Thuram, 29 · Inter · CF · Complete forward · Moneyball Score 73

Marcus Thuram, 29, plays as a centre-forward for Inter in Serie A. Strongest for his role in shots and expected goals. Weakest in big chances missed. Moneyball Scout, the engine behind our Scouting Players Research, rates him against every centre-forward in Europe's top five leagues - and this is what he does better than almost all of them.

Expected goals 86Goals 85Shots 94Shots on target 44Shot quality 61Aerial duels won 75Duels won 80Key passes 74Big chances missed 1

Percentile against his position on each figure: 50 is the average centre-forward, 90 the top tenth.

Positions he can play

  • ST · Centre-forward Natural, 73

Where he is strongest

FigureHis numberBetter than
Shots4.63 / 9094%
Expected goals0.74 / 9086%
Goals0.98 / 9085%
Duels won6.34 / 9080%
Aerial duels won2.93 / 9075%

Roles he suits

  • ★★★★½ Shadow striker Second striker
  • ★★★★ Complete forward Centre-forward
  • ★★★★ Poacher Centre-forward

Scout's notes: High shot volume, Gets into scoring positions, Clinical finisher.

In Moneyball Scout
  • What Marcus Thuram is worth on the market, and the most a club should pay
  • How many league points he would add to your club (Win-Rate Impact)
  • The players who play like him, cheaper - the Replacement Finder
  • His chemistry with your squad, his fit with your style, his projection by age

Open Marcus Thuram's full file Moneyball Scout from $39 a month

Inter Milan vs Shakhtar Donetsk prediction

Moneyball's model expects about 3.5 goals - 2.35 for Inter Milan and 1.17 for Shakhtar Donetsk - with over 2.5 goals at 68% and both teams scoring at 63%. Inter Milan have the stronger numbers, and we expect them to make home advantage count.

Prediction: Inter Milan 2-1 Shakhtar Donetsk

The full model, every line of this match, in the Match Centre

Inter Milan vs Shakhtar Donetsk betting tips

  1. Tip 1: Inter Milan to win 75% on the bookmakers' prices, with their margin taken out
  2. Tip 2: Over 2.5 goals 68% by the model, 3.52 goals expected
  3. Tip 3: Both teams to score: yes 63% by the model
  4. Tip 4: Over 3.5 cards the two sides average 5.1 cards a match between them
  5. Tip 5: Over 8.5 corners 9.7 corners a match between them

Statistical leanings from the data, not certainties. 18+ only, where betting is legal; never stake more than you can afford to lose.

Moneyball's pick

The Dixon-Coles and xG model prices every line of this match: the win, draw and loss probabilities, fair odds and the expected value of each handicap and goals line. The full analysis of this match is part of Moneyball Premium.

Open Inter Milan vs Shakhtar Donetsk in the Match Centre Follow it live

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Inter Milan vs Shakhtar Donetsk: questions and answers

When is Inter Milan vs Shakhtar Donetsk?

Inter Milan vs Shakhtar Donetsk is on Wednesday 21 October 2026, in UEFA Champions League Gameweek 3.

Where is Inter Milan vs Shakhtar Donetsk played?

At Stadio Giuseppe Meazza, Milano, Inter Milan's home ground.

Who will win Inter Milan vs Shakhtar Donetsk?

Inter Milan are the favourites: Inter Milan 75%, draw 15%, Shakhtar Donetsk 10%. Our prediction is Inter Milan 2-1 Shakhtar Donetsk.

Who is the player to watch in Inter Milan vs Shakhtar Donetsk?

Marcus Thuram of Inter: a complete forward with a Moneyball Score of 73 against every centre-forward in Europe's top five leagues.

How many goals will there be in Inter Milan vs Shakhtar Donetsk?

Moneyball's model expects about 3.5 goals, with over 2.5 goals at 68%.

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Moneyball Odds is a statistical analysis site, not a bookmaker. No model predicts football reliably. For readers aged 18 and over, where betting is legal.